Aerosolized 3-Bromopyruvate Inhibits Lung Tumorigenesis without Causing Liver Toxicity
نویسندگان
چکیده
منابع مشابه
Aerosolized 3-bromopyruvate inhibits lung tumorigenesis without causing liver toxicity.
3-Bromopyruvate, an alkylating agent and a well-known inhibitor of energy metabolism, has been proposed as a specific anticancer agent. However, the chemopreventive effect of 3-bromopyruvate in lung tumorigenesis has not been tested. In this study, we investigated the chemopreventive activity of 3-bromopyruvate in a mouse lung tumor model. Benzo(a)pyrene was used to induce lung tumors, and 3-br...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2012
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-11-0338